RNDr. Pavel Babica, Ph.D.

RNDr. Pavel Babica, Ph.D.

Specializace:

  • analytické stanovení cyanotoxinů
  • ekotoxikologie cyanotoxinů
  • hodnocení rizik
  • epigenetické mechanismy v karcinogenezi

Kontakty:

e-mail:
tel.:+420 530 506 744

Vzdělání:

  • Mgr. v oboru Ekotoxikologie (PřF MU v Brně, 2002)      
  • RNDr. v oboru Ekotoxikologie (PřF MU v Brně, 2005)      
  • Ph.D. v oboru Chemie životního prostředí (PřF MU v Brně, 2006)

Zkušenosti, další aktivity, ocenění:

  • Botanický ústav AV ČR - vědecký pracovník (od 2003)
  • Michigan State University, Food Safety and Toxicology Center, East Lansing, USA - postdoktorální stáž (prosinec 2006 – červen 2010)
  • cena děkana Přírodovědecké fakulty Masarykovy univerzity pro studenty doktorských studijních programů (2006)
  • cena rektora Masarykovy univerzity pro studenty doktorských studijních programů (2007)
  • člen Society of Toxicology - Michigan Chapter, člen International Society for the Study of Harmful Algae

 

Vybrané publikace

Mezinárodní odborné časopisy:

  • Jančula, D., Straková, L., Sadílek, J., Maršálek, B., Babica, P. (2014): Survey of cyanobacterial toxins in Czech water reservoirs – the first observation of neurotoxic saxitoxins. Environmental Science and Pollution Research 21(13): 8006-8015.
  • Jančula, D., Maršálek, B., Babica, P. (2013): Photodynamic effects of 31 different phthalocyanines on a human keratinocyte cell line. Chemosphere 93(6): 870-874.
  • Osgood, R.S., Upham, B.L., Hill III, T., Helms, K.L., Velmurugan, K., Babica, P., Bauer, A.K. (2013): Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure. Plos One 8(6): e65150.
  • Nováková, K., Bláha, L., Babica, P. (2012): Tumor promoting effects of cyanobacterial extracts are potentiated by anthropogenic contaminants – evidence from in vitro study. Chemosphere 89(1): 30-37.
  • Bártová, K., Hilscherová, K., Babica, P., Maršálek, B. (2011): Extract of Microcystis water bloom affects cellular differentiation in filamentous cyanobacterium Trichormus variabilis (Nostocales, Cyanobacteria). Journal of Applied Phycology 23(6): 967-973.
  • Bártová, K., Hilscherová, K., Babica, P., Maršálek, B., Bláha, L. (2011): Effects of microcystin and complex cyanobacterial samples on growth and oxidative stress paramaters in green alga Pseudokirchneriella subcapitata and comparison with the effects of model oxidative stressor, herbicide paraquat. Environmental Toxicology 26(6): 641-648.
  • Nováková, K., Babica, P., Adamovský, O., Bláha, L. (2011): Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures. Toxicon 58(1): 76-84.
  • Bláha, L., Babica, P., Hilscherová, K., Upham, B. (2010): Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - indications of novel tumor promoting cyanotoxins? Toxicon 55(1): 126-134.
  • Alpatova, A.L., Shan, W., Babica, P., Rogensues, A. R., Masten, S. J., Drown, E., Mohanty, A. K., Upham, B. L., Alocilja, E. C., Tarabara, V. V. (2010): Single-walled carbon nanotubes dispersed in aqueous media via non-covalent functionalization: Effect of dispersant on the stability, cytotoxicity, and epigenetic toxicity of nanotube suspensions. Water Research 44: 505-520.   
  • Bláha, L., Bláhová, L., Kohoutek, J., Adamovský, O., Babica, P., Maršálek, B. (2010): Temporal and spatial variability of cyanobacterial toxins microcystins in three interconnected freshwater reservoirs. Journal of the Serbian Chemical Society 75(9):1303-1312.   
  • Upham, B., Park, J.S., Babica, P., Sovadinová, I., Rummel, A., Trosko, J., Hirose, A., Hasegawa, R., Kanno, J., Sai, K. (2009): Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems. Environmental Health Perspectives 117(4): 545-551.   
  • Bláha L., Babica, P., Maršálek, B. (2009): Toxins produced in cyanobacterial water blooms - toxicity and risks. Interdisciplinary Toxicology 2:36-41.   
  • Bláhová, L., Babica, P., Adamovský, O., Kohoutek, J., Maršálek B., Bláha, L. (2008): Analyses of cyanobacterial toxins microcystins and cylindrospermopsin in water bloom samples and drinking waters from the Czech Republic and evaluation of health risks. Environmental Chemical Letters 6(4): 223-227.   
  • Pašková, V., Adamovský,  O., Pikula, J., Skočovská, B., Banďouchová, H., Horáková, J., Babica, P., Maršálek, B., Hilscherová, K. (2008): Detoxification and oxidative stress responses along with microcystins accumulation in Japanese quail exposed to cyanobacterial biomass. Science of Total Environment 398(1-3):34-47.      
  • Kohoutek, J., Babica, P., Bláha, L., Maršálek, B. (2008): A novel approach for monitoring of cyanobacterial toxins - development and evaluation of the passive sampler for microcystins. Analytical and Bioanalytical Chemistry 390(4):  1167-1172.      
  • Bernardová, K., Babica, P., Maršálek, B., Bláha, L. (2008): Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga. Journal of Applied Toxicology 28(1): 72-77.      
  • Upham, B., Bláha, L., Babica, P., Park, J.S., Sovadinová, I., Pudrith, C., Rummel, A., Weis, L.,Sai, K., Tithof, P., Guzvic, M., Vondráček, J., Machala, M., Trosko, J. (2008): Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C. Cancer Science 99(4): 696-705.      
  • Babica, P., Hilscherová, K., Bártová, K., Maršálek, B., Bláha, L. (2007): Effects of dissolved microcystins on growth of planktonic photoautotrophs. Phycologia 46(2): 137-142.      
  • Bláhová, L., Babica, P., Maršálková, E., Maršálek, B., Bláha, L. (2007): Concentrations and seasonal trends of extracellular microcystins in freshwaters of the Czech Republic - results of the national monitoring program. CLEAN - Soil, Air, Water 35(4): 348-354.      
  • Skočovská, B., Hilscherová, K., Babica, P., Adamovský, O., Banďouchová, H., Horáková, J., Knotková, Z., Maršálek, B., Pašková, V., Pikula, J. (2007): Effects of cyanobacterial biomass on the Japanese quail. Toxicon 49(7): 793-803.      
  • Adamovský, O., Kopp, R., Hilscherová, K., Babica, P., Palíková, M., Pašková, V., Navrátil, S., Maršálek, B., Bláha, L. (2007): Microcystin kinetics (bioaccumulation, elimination) and biochemical responses in common carp and silver carp exposed to toxic cyanobacterial blooms. Environmental Toxicology and Chemistry 26(12): 2687-2693.      
  • Palíková, M., Krejčí, R., Hilscherová, K., Babica, P., Navrátil, S., Kopp, R., Bláha, L. (2007): Effect of different cyanobacterial biomasses and their fractions with variable microcystin content on embryonal development of carp (Cyprinus carpio L.). Aquatic Toxicology 81(3): 312-318.      
  • Palíková, M., Krejčí, R., Hilscherová, K., Burýšková, B., Babica, P., Navrátil, S., Kopp, R., Bláha, L. (2007): Effects of different oxygen saturation to activity of complex biomass and aqueous crude extract of cyanobacteria during embryonal development in carp (Cyprinus carpio L.). Acta Veterinaria Brno 76(2): 291-299.
  • Babica, P., Kohoutek, J., Bláha, L., Adamovský, O., Maršálek B. (2006): Evaluation of extraction approaches linked with ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material content. Analytical and Bioanalytical Chemistry 385(8): 1545-1551.
  • Pavlova, V., Babica, P., Todorova, D., Bratanova, Z., Maršálek B. (2006): Contamination of some reservoirs and lakes in Republic of Bulgaria by microcystins. Acta Hydrochimica et Hydrobiologica 34(5): 437-441.
  • Burýšková, B., Hilscherová, K., Babica, P., Vršková, D., Maršálek, B., Bláha, L. (2006): Toxicity of complex cyanobacterial samples and their fractions in Xenopus laevis embryos and the role of microcystins. Aquatic Toxicology 80(4): 346-354.
  • Addico, G., Hardege, J., Komárek, J., Babica, P., de Graft-Johnson, K.A.A. (2006): Cyanobacteria species identified in the Weija and Kpong reservoirs, Ghana, and their implications for drinking water quality with respect to microcystin. African Journal of Marine Science 28(2): 451-456.
  • Zeisbergerová, M., Košťál, V., Šrámková, M., Babica, P., Bláha, L., Glatz, Z., Kahle, V. (2006): Separation of microcystins on monolithic electrochromatography columns. Journal of Chromatography B 841(1-2): 140-144.
  • Kopp, R., Mareš, J., Kubíček, Z., Babica, P. (2005): The influence of toxic cyanobacterial water blooms on the hematological indicators of silver carp (Hypophthalmichthys molitrix Val.). Oceanological and Hydrobiological Studies 34(Suppl. 3): 85-92.
  • Babica P., Bláha L., Maršálek B. (2006): Exploring the natural role of microcystins - review of effects on photoautotrophic organisms. Journal of Phycology 42(1): 9-20.
  • Babica, P., Bláha, L., Maršálek, B. (2005): Removal of microcystins by phototrophic biofilms: a microcosm study. Environmental Science and Pollution Research 12(6): 369-374.
  • Bláha, L., Sabater, S., Babica, P., Vilalta, E., Maršálek, B. (2004): Geosmin occurrence in riverine cyanobacterial mats: is it causing a significant health hazard? Water Science and Technology 49(9): 307-312.

Ostatní:

  • Maršálek, B., Bláha, L., Bláhová, L., Babica, P. (2005): Czech Republic: Management and regulation of cyanobacteria and cyanotoxins. In: Current approaches to cyanotoxin risk assessment, risk management and regulations in different countries (Chorus I. - ed.), WaBoLu - Hefte 02-05, Federal Environmental Agency (Umweltbundesamt), Dessau, Germany, pp. 37-39.
  • Šejnohová, L., Komárek, J., Zapomělová, E., Pumann, P., Maršálek, B., Babica, P. (2005): Interaktivní klíč pro určování sinic vodních květů. CCT & JU České Budějovice & SZU Praha, Czech Republic, 343 pp.
  • Maršálek, B., Bláha, L., Babica, P. (2003): Analyses of microcystins in the biomass of Pseudanabaena limnetica collected in Znojmo reservoir. Czech Phycology 3: 195-197.


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